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Tutorials

These tutorials build up from simply viewing images to full single-cell analysis. You don't need to read them in order, but each section assumes you're comfortable with the one before it.


A quick note on cell tables

UELer works in two modes, and it's worth knowing which one you're in:

  • Without a cell table, UELer is an image viewer. You can browse channels, overlay masks and annotations, capture regions of interest, and batch-export images.
  • With a cell table loaded, UELer becomes a linked single-cell explorer — scatter plots, histograms, heatmaps, clustering, and the cell gallery all light up and stay synchronized with the image.

This isn't just a suggestion: the viewer only loads the analytical plugins once a cell table is present. With no cell table, the right panel shows just the ROI manager and Batch export plugins. See Working with a Cell Table for how to load one.


Part 1 · Essentials

Everything here works on images alone — no cell table required.

Tutorial What you'll learn
Basic Usage Launch the viewer, pick an FOV, select channels, and navigate
User Interface A reference map of the four regions and every left-panel control
Display Settings Set the viewer up so it shows your data correctly — pixel size, cache, downsampling, contrast
Regions of Interest Capture, tag, and browse ROIs that persist across sessions
Map Mode Stitch multiple FOVs into one spatial canvas (opt-in feature)
Batch Export Export full FOVs, ROIs, and single-cell crops to image files

Part 2 · Single-Cell Analysis

These features require a cell table (a per-cell feature CSV, e.g. from ark-analysis).

Tutorial What you'll learn
Working with a Cell Table Load a table, understand linked selection, and use the cell gallery
Scatter & Histogram Explore marker distributions with linked brushing
Clustering & Annotation Heatmaps, FlowSOM clustering, and saving annotation checkpoints

New here?

Start with Basic Usage, then skim the User Interface reference. Before you trust what you see — or export it — walk through Display Settings once for the dataset. Then, with a cell table, move on to Working with a Cell Table.